Saturday, August 22, 2015

Why haven't I Heard of SPG Blocks Before?

The Sphenopalatine Ganglion Block has been used for while over a century.  So, why does it seem like nobody has ever heard of it until recently and why is it changing now.

According to an article in the Pain Practitioner in 2004, "Sphenopalatine Ganglion Blockade: A Review and Proposed Modification of the Transnasal Technique Report of Technique" by  Robert E. Windsor, MD, and Scott Jahnke, DO  the accepted uses of "the SPG block are sphenopalatine neuralgia, trigeminal neuralgia, atypical facial pain, acute migraine, acute and chronic cluster headaches, herpes zoster involving the ophthalmic nerve and a variety of other facial neuralgias. The mechanism by which intranasal lidocaine alleviates the pain is not fully understood, however it is believed to reverse the parasympathetic contribution to intracranial vasodilatation by blocking the sphenopalatine ganglion. It is not considered a first line treatment for low back pain, sciatica, arthritis, or angina despite several studies showing statistical benefit."

This article shows that there are a wide variety of accepted uses of the SPG Block.  The best selling book "Miracles on Park Avenue" basically described a doctor who utilized the SPG block on all comers for chronic pain with amazing results in problems like Fibromyalgia.  One problem  with the block was it used an aqueous solution of cocaine that is highly regulated by the DEA and only ENTs routinely used it in practice.

Sluder first used the term sphenopalatine neuralgia in 1909. He described unilateral facial pain associated with signs of parasympathetic hyperactivity such as mucosal congestion, rhinorrhea, and lacrimation. Many considered this the first description of TMJ disorders without the joint component.
TMJ Disorders are frequently referred to as "The Great Imposter" because they mimic so many other conditions.

 Precacci et al found lessening of trigger point pain following SPG blocks on patients suffering from complex regional pain syndrome. This effect on trigger points is without risk of side effects compared to new drugs treating Fibromyalgia such as Lyrica.  Fibromyalgia is not cured by SPG Blocks but symptoms are vastly improved.  The connection of Fibromyalgia to Sleep by Moldofsky firmly placed it as an autonomic nervous disorder.  The SPG Block is like a reset button for the sympathetic and parsympathetice components of the autonomic nervous system.

Boston University School of Medicine  utilized SPG blocks with topical application of 10% cocaine solution and found improvement in acute low back and musculoskeletal pain.  There was significant improvement compared to plcebo and patients also showed increases in mobility.

Cluster Headaches were shown to be aborted by Barre  in 1982( after the topical application of cocaine.  This was the first instance I found of patients being taught to apply the anesthetic at home.

Kittrelle et al showed in 1985 that lidocaine had equivlant effects to cocaine in aborting acute cluster headaches.

 Berger et al in 1986  used of 4% topical Xylocaine and found it equal  to 10% cocaine and better than placebo for the relief of pain in patients with chronic lower back pain.

The SPG Block is back after being utilized by only a small number of Dentists and Physicians for several years.  A small number of dentists became the became the defacto experts in utilizing this block.  I learned from Jack Haden in Kansas City initially but my friend Dr Barry Glassman and Larry Lockerman also increased my knowledge.  I became obsessed with the literature because my wife had frequent pain from endometriosis / Endomyosis and the SPG Block removed the issue of severe pain.  Later , after being diagnosed with stage four ovarian cancer we again found SPG Blocks to be helpful in controlling the pain. (not the disease)

In the last few years three companies have brought devices to market to simplify SPG Blocks.  The TX360, the Sphenocath and Allevio all work by targeting squirts of anesthetic over the area of nasal mucosa covering the Ganglion.

I prefer the continuous feed method obtained with a hollow swab continually delivering anaesthetic over a period of time.  My preference is based on it being highly effective, and as  Barre found  in 1982 patients could be taught to self administer treatment at home.  This method is also extremely ineffective drastically lowering costs to both insurance companies and to patients.

When a patient is in the middle of a severe Pain episode the intra-oral injection or facial injection is most effective and will give the fastest relief.

I currently teach courses to Physicians and Dentists on administration of SPG Blocks.  I also teach patients how to utilize this excellent treatment to improve their quality of life.  When patients are in a doctors office their quality of life is lessened, when they can use SPG Blocks to turn of their pain without disrupting their lives the truly have an excellent treatment.

To learn more about treatment with SPG Blocks contact me thru www.ThinkBetterLife.com.

I utilize SPG Blocks along with TENS, Diagnostic neuromuscular orthotics, neuromuscular dentistry, trigger point injections, transcranial neurotransmitter modulation, spray and stretch, NuCalm and other techniques to restore quality of life as rapidly as possible.

Patient Testimonials are available on the ICCMO website:
  http://occlusiontmjauthority.com/dr-ira-shapira-testimonials/   and at

There is an extensive Bibliography from PubMed at the end of this article.

Elahi F, Reddy CG.
Pain Physician. 2015 May-Jun;18(3):E403-9.

2.
3.
Kent S, Mehaffey G.
Am J Emerg Med. 2015 Mar 14. pii: S0735-6757(15)00168-0. doi: 10.1016/j.ajem.2015.03.024. [Epub ahead of print] No abstract available.

4.
Schaffer JT, Hunter BR, Ball KM, Weaver CS.
Ann Emerg Med. 2015 May;65(5):503-10. doi: 10.1016/j.annemergmed.2014.12.012. Epub 2015 Jan 7.

5.
Elahi F, Ho KW.
Case Rep Neurol Med. 2014;2014:923516. doi: 10.1155/2014/923516. Epub 2014 Sep 29.
6.
Cohen S, Ramos D, Grubb W, Mellender S, Mohiuddin A, Chiricolo A.
Reg Anesth Pain Med. 2014 Nov-Dec;39(6):563. doi: 10.1097/AAP.0000000000000172. No abstract available.

7.
Cady R, Saper J, Dexter K, Manley HR.
Headache. 2015 Jan;55(1):101-16. doi: 10.1111/head.12458. Epub 2014 Oct 23.

8.
Grant GJ, Schechter D, Redai I, Lax J.
Int J Obstet Anesth. 2014 Aug;23(3):292-3. doi: 10.1016/j.ijoa.2014.04.010. Epub 2014 May 10. No abstract available.

9.
Miller S, Matharu M.
Curr Pain Headache Rep. 2014;18(8):438. doi: 10.1007/s11916-014-0438-z. Review.

10.
Kastler A, Cadel G, Comte A, Gory G, Piccand V, Tavernier L, Kastler B.
Neuroradiology. 2014 Jul;56(7):589-96. doi: 10.1007/s00234-014-1354-y. Epub 2014 Apr 26.

11.
Prakash S, Patell R.
Curr Pain Headache Rep. 2014 Apr;18(4):407. doi: 10.1007/s11916-014-0407-6. Review.

12.
Zarembinski C, Graff-Radford S.
Pain Med. 2014 Feb;15(2):329-32. doi: 10.1111/pme.12302. Epub 2013 Dec 17.

13.
Shimizu T.
Rinsho Shinkeigaku. 2013;53(11):1131-3. Review. Japanese.

14.
Candido KD, Massey ST, Sauer R, Darabad RR, Knezevic NN.
Pain Physician. 2013 Nov-Dec;16(6):E769-78.

15.
Tepper SJ, Stillman MJ.
Headache. 2013 Jul-Aug;53(7):1183-90. doi: 10.1111/head.12148. Epub 2013 Jun 28. Review.

16.
Rodman R, Dutton J.
Int Forum Allergy Rhinol. 2012 Jul-Aug;2(4):325-30. doi: 10.1002/alr.21035. Epub 2012 Apr 5.

17.
Ebbeling MB, Oomen KP, de Ru JA, Hordijk GJ, Bleys RL.
Am J Rhinol Allergy. 2012 Jan-Feb;26(1):e40-5. doi: 10.2500/ajra.2012.26.3697.

18.
DeMaria S Jr, Govindaraj S, Chinosorvatana N, Kang S, Levine AI.
Am J Rhinol Allergy. 2012 Jan-Feb;26(1):e23-7. doi: 10.2500/ajra.2012.26.3709.
19.
Cho DY, Drover DR, Nekhendzy V, Butwick AJ, Collins J, Hwang PH.
Int Forum Allergy Rhinol. 2011 May-Jun;1(3):212-8. doi: 10.1002/alr.20040. Epub 2011 Apr 13.

20.
Treatment Guideline Subcommittee of the Taiwan Headache Society, Chen PK, Chen HM, Chen WH, Chen YY, Fuh JL, Lee LH, Liao YC, Lin KC, Tseng HP, Tsai JJ, Wang PJ, Wang SJ, Yang CP, Yiu CH, Wu ZA.
Acta Neurol Taiwan. 2011 Sep;20(3):213-27. Review. Chinese.


Pipolo C, Bussone G, Leone M, Lozza P, Felisati G.
Neurol Sci. 2010 Jun;31 Suppl 1:S197-9. doi: 10.1007/s10072-010-0325-2.

22.
Rodman R, Dutton J.
Int Forum Allergy Rhinol. 2012 Jul-Aug;2(4):325-30. doi: 10.1002/alr.21035. Epub 2012 Apr 5.

24.
Varghese BT, Koshy RC.
J Laryngol Otol. 2001 May;115(5):385-7.

25.
Saade E, Paige GB.
Reg Anesth. 1996 Jan-Feb;21(1):68-70.

26.
Murty PS, Prasanna A.
Indian J Otolaryngol Head Neck Surg. 1998 Jan;50(1):99-105. doi: 10.1007/BF02996789.

27.
Saberski L, Ahmad M, Wiske P.
Headache. 1999 Jan;39(1):42-4.

28.
Ferrante FM, Kaufman AG, Dunbar SA, Cain CF, Cherukuri S.
Reg Anesth Pain Med. 1998 Jan-Feb;23(1):30-6.

29.
Manahan AP, Malesker MA, Malone PM.
Nebr Med J. 1996 Sep;81(9):306-9.

30.
Silverman DG, Spencer RF, Kitahata LM, O'Connor TZ.
Reg Anesth. 1993 Nov-Dec;18(6):356-60.

31.
Peterson JN, Schames J, Schames M, King E.
Cranio. 1995 Jul;13(3):177-81.

32.
Lebovits AH, Alfred H, Lefkowitz M.
Clin J Pain. 1990 Jun;6(2):131-6.

33.
34.
Prasanna A, Murthy PS.
J Pain Symptom Manage. 1997 Jun;13(6):332-8.

35.
36.
Prasanna A, Murthy PS.
Clin J Pain. 1993 Jun;9(2):135-7. No abstract available.

37.
Spencer RF.
Reg Anesth. 1997 Sep-Oct;22(5):483-4. No abstract available.

38.
Morelli N, Mancuso M, Felisati G, Lozza P, Maccari A, Cafforio G, Gori S, Murri L, Guidetti D.
Cephalalgia. 2010 Mar;30(3):365-7. doi: 10.1111/j.1468-2982.2009.01882.x. Epub 2010 Feb 1.

39.
Prasanna A, Murthy PS.
Reg Anesth. 1993 Mar-Apr;18(2):139-40. No abstract available.

40.
Hwang JH, Liu CM, Liu TC, Hsu MC.
Laryngoscope. 2003 Aug;113(8):1423-4. No abstract available.

42.
Prasanna A, Murthy PS.
J Pain Symptom Manage. 1993 Apr;8(3):125. No abstract available.

43.
Cohen S, Trnovski S, Zada Y.
Anaesthesia. 2001 Jun;56(6):606-7. No abstract available.

44.
Waldman SD.
Reg Anesth. 1993 Sep-Oct;18(5):274-6. No abstract available.

45.
46.
Yang lY, Oraee S.
Pain Physician. 2006 Apr;9(2):131-4.

47.
Henneberger JT, Menk EJ, Middaugh RE, Finstuen K.
South Med J. 1988 Jul;81(7):832-6.

48.
Felisati G, Arnone F, Lozza P, Leone M, Curone M, Bussone G.
Laryngoscope. 2006 Aug;116(8):1447-50.

49.
Narouze S, Kapural L, Casanova J, Mekhail N.
Headache. 2009 Apr;49(4):571-7. doi: 10.1111/j.1526-4610.2008.01226.x. Epub 2008 Sep 9.

50.
Olszewska-Ziaber A, Ziaber J, Rysz J.
Otolaryngol Pol. 2007;61(3):319-21. Polish.
51.
Varghese BT, Koshy RC, Sebastian P, Joseph E.
Palliat Med. 2002 Sep;16(5):447-8. No abstract available.

52.
Ciammitti B, Tesoro S, Carloni D, Bifarini G.
Minerva Anestesiol. 1991 Sep;57(9):538-9. Italian. No abstract available.

54.
Tepper SJ, Stillman MJ.
Headache. 2013 Jul-Aug;53(7):1183-90. doi: 10.1111/head.12148. Epub 2013 Jun 28. Review.

55.
Quevedo JP, Purgavie K, Platt H, Strax TE.
Arch Phys Med Rehabil. 2005 Feb;86(2):335-7.

57.
Grégoire A, Clair C, Delabrousse E, Aubry R, Boulahdour Z, Kastler B.
J Radiol. 2002 Sep;83(9 Pt 1):1082-4. French.
59.
Devoghel JC.
Acta Anaesthesiol Belg. 1981;32(1):101-7.
60.
Vallejo R, Benyamin R, Yousuf N, Kramer J.
Pain Pract. 2007 Mar;7(1):44-6. No abstract available.


Brown CR.
Pract Periodontics Aesthet Dent. 1997 Jan-Feb;9(1):99-100. No abstract available.
62.
Shuster MA, Natsvlishvili VI, Aleksandrov EN.
Vestn Otorinolaringol. 1979 Nov-Dec;(6):45-9. Russian. No abstract available.
63.
Janzen VD, Scudds R.
Laryngoscope. 1997 Oct;107(10):1420-2.
64.
Miller S, Matharu M.
Curr Pain Headache Rep. 2014;18(8):438. doi: 10.1007/s11916-014-0438-z. Review.
65.
Shimizu T.
Rinsho Shinkeigaku. 2013;53(11):1131-3. Review. Japanese.
66.
Yarnitsky D, Goor-Aryeh I, Bajwa ZH, Ransil BI, Cutrer FM, Sottile A, Burstein R.
Headache. 2003 Jul-Aug;43(7):704-14.
67.
Treatment Guideline Subcommittee of the Taiwan Headache Society, Chen PK, Chen HM, Chen WH, Chen YY, Fuh JL, Lee LH, Liao YC, Lin KC, Tseng HP, Tsai JJ, Wang PJ, Wang SJ, Yang CP, Yiu CH, Wu ZA.
Acta Neurol Taiwan. 2011 Sep;20(3):213-27. Review. Chinese.
69.
Levin M.
Neurotherapeutics. 2010 Apr;7(2):197-203. doi: 10.1016/j.nurt.2010.03.001. Review.
70.
Spacek A, Hanl G, Groiss O, Koinig H, Kress HG.
Wien Med Wochenschr. 1998;148(19):447-9. German.
71.
Robiony M, Demitri V, Costa F, Politi M, Cugini U.
Br J Oral Maxillofac Surg. 1998 Oct;36(5):389-91.

72.
Grégoire PC.
Can Nurse. 1991 Oct;87(9):33-5. French.
73.
Kanai A, Suzuki A, Kobayashi M, Hoka S.
Br J Anaesth. 2006 Oct;97(4):559-63. Epub 2006 Aug 1.

SPG Nerve Block catheter Bibliography CHRONIC DAILY HEADACHE AND MIGRAINE
 Agency of Healthcare Research and Quality, a division of the Department of Health & Human Services,
 “Over 3 Million Look to Hospitals for Headache Relief, Particularly for Migraines,”
 http://www.ahrq.gov/news/nn/nn050411.htm Archibald N, et al.
 Resource Utilization and Costs of Care for Treatment of Chronic Headache. Rockville (MD): 
Agency for Health Care Policy and Research (US); February 1999,
 http://www.ncbi.nlm.nih.gov/books/NBK45258/ Castillo, J, et al.
 Epidemiology of Chronic Daily Head in the General Population, Headache, March 1999, 
http://www.ncbi.nlm.nih.gov/pubmed/15613213 CIA World Fact Book,
https://www.cia.gov/library/publications/the-worldfactbook/ fields/2002.html Coeytaux, RR, et al.
 Chronic daily headache in a primary care population: prevalence and headache impact test scores. 
Headache. 2007 Jan; 47(1): 7-12, http://www.ncbi.nlm.nih.gov/pubmed/17355488 Cohen, S, et al. 
A new interest in an old remedy for headache and backache for our obstetric patients: a sphenopalatine ganglion block. 
Anaesthesia, 2000, 56, 606- 07, http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.2001.2094-34.x/full 
Evans, RW, Diagnostic Testing for Chronic Daily Headache, 
Current Pain and Headache Reports 2007, 11:47-52,